Broad Institute of MIT and Harvard, USA
Konrad Karczewski is a genome scientist, currently an Assistant Professor in the Center for Genomic Medicine at MGH and an Associate Member at the Broad Institute. Konrad received his undergraduate degree in Molecular Biology from Princeton University and his PhD in Biomedical Informatics from Stanford University, where he studied how regulatory variation influences human biology and disease. In his postdoctoral research, he built tools for variant interpretation (LOFTEE) that are widely used across the field, as well as the world’s largest public datasets of genetic variation (gnomAD) that provide critical insight into gene and variant function, as well as browser infrastructures to serve these results to the community. His lab’s research is focused on assembling and analyzing massive public datasets of genetic variation, developing innovative strategies to interpret disease variants, and creating open-access resources that serve the global scientific community. His work spans from basic science to clinical applications, aiming to improve our ability to identify causal disease variants and deepen our understanding of human genetics.